The exome represents less than 2% of the human genome, but contains ~85% of known disease-causing variants, making whole-exome sequencing a cost-effective alternative to whole-genome sequencing.
With exome sequencing, you can investigate the protein coding regions of the genome when sequencing an entire genome is not practical or necessary. It can efficiently identify variants across a wide range of applications, including population genetics, genetic disease, and cancer studies.
Illumina offers comprehensive exome sequencing solutions, from library preparation to data analysis.
Our exome enrichment and sequencing kits include Nextera Rapid Capture Exome, an integrated solution for library preparation and exome enrichment of up to 96 samples in only 1.5 days. These kits deliver comprehensive coverage of expertly selected exonic content. Choose the format that best fits your studies and add custom content for specific regions of interest.
Illumina sequencers deliver industry-leading accuracy, enabling you to confidently identify true coding variants. Within the Illumina sequencing ecosystem, you can scale projects to sequence from one to hundreds of exomes per run.
Our exome sequencing data analysis solutions include the BaseSpace genomics computing environment. BaseSpace removes much of the complexity from the typical informatics workflow without requiring extra analysis equipment. BaseSpace offers apps for exome analysis, as well as a large collection of apps for data visualization, downstream analysis, and sharing.
Many cancer causing variants are found within exonic regions. Cancer exome sequencing enables you to take a closer look.
New to NGS? See how you can gain insight into the genome with next-generation sequencing.
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